A complete list of John DiPersio’s publications and funding sources can be found here (NCBI)

+ 2024

Blinatumomab consolidation post-autologous stem cell transplantation in patients with diffuse large B-cell lymphoma

Ghobadi A, Foley NC, Cohen J, Rettig MP, Cashen AF, Gehrs L, Christ S, Street E, Wallace N, Ritchey J, Neha M-S, Westervelt P, Fehniger TA, Kahl B, Bartlett NL, DiPersio JF, 2024 Feb 13 in Blood Advances; 8(3):513-522.

Targeting CXCR4, VLA-4 and CXCR2 for Hematopoietic Stem Cell Mobilization

Cancilla, D, Rettig MP, Karpova D, Thakellapalli H, Singh M, Meyers MJ, Ruminski PG, Christ S, Chendamarai E, Gao F, Gehrs L, Ritchey JK, Prinsen MJ, DiPersio JF, 2024 Jan 8 in Blood Advances; ahead of print.

+ 2023

A Multicenter Phase 2 Clinical Trial of 10-Day Decitabine, Dose-Escalated Donor Lymphocyte Infusion, and Ruxolitinib for Relapsed Acute Myeloid Leukemia and Myelodysplastic Syndromes after Allogeneic Hematopoietic Cell Transplantation

Rashidi, A., Huselton, E. J., Stefanski, H. E., DeFor, T. E., Shanley, R., Choi, J., DiPersio, J. F., Juckett, M., Miller, J. S., Weisdorf, D. J. & Schroeder, M. A., May 2023, In: Transplantation and Cellular Therapy. 29, 5, p. 328.e1-328.e6

Anti-myeloma efficacy of CAR-iNKT is enhanced with a long-acting IL-7, rhIL-7-hyFc

O’Neal, J., Cooper, M. L., Ritchey, J. K., Gladney, S., Niswonger, J., González, L. S., Street, E., Haas, G. J., Carter, A., Amayta, P. N., Gao, F., Lee, B. H., Choi, D., Berrien-Elliott, M., Zhou, A., Fehniger, T. A., Rettig, M. P. & DiPersio, J. F., Oct 24 2023, In: Blood Advances. 7, 20, p. 6009-6022 14 p.

An “off-the-shelf” CD2 universal CAR-T therapy for T-cell malignancies

Xiang, J., Devenport, J. M., Carter, A. J., Staser, K. W., Kim, M. Y., O’ Neal, J., Ritchey, J. K., Rettig, M. P., Gao, F., Rettig, G., Turk, R., Lee, B. H., Cooper, M. L. & DiPersio, J. F., Dec 2023, In: Leukemia. 37, 12, p. 2448-2456 9 p.

Apolipoprotein M Attenuates Anthracycline Cardiotoxicity and Lysosomal Injury

Guo, Z., Valenzuela Ripoll, C., Picataggi, A., Rawnsley, D., Ozcan, M., Chirinos, J. A., Chendamarai, E., Girardi, A., Riehl, T., Evie, H., Diab, A., Kovacs, A., Hyrc, K., Ma, X., Asnani, A., Shewale, S. V., Scherrer-Crosbie, M., Cowart, L. A., Parks, J. S., Zhao, L., & 14 others, Mar 2023, In: JACC: Basic to Translational Science. 8, 3, p. 340-355 16 p.

A systematic framework for predictive biomarkers in immune effector cell-associated neurotoxicity syndrome

Butt, O. H., Zhou, A. Y., Ances, B. M., DiPersio, J. F. & Ghobadi, A., 2023, In: Frontiers in Neurology. 14, 1110647.

Baricitinib with cyclosporine eliminates acute graft rejection in fully mismatched skin and heart transplant models

Abboud, R., Kim, S., Staser, K., Jayasinghe, R. G., Lim, S., Amatya, P., Frye, C. C., Kopecky, B., Ritchey, J., Gao, F., Lavine, K., Kreisel, D., DiPersio, J. F. & Choi, J., 2023, In: Frontiers in immunology. 14, 1264496.

Epigenetic regulation during cancer transitions across 11 tumour types

Terekhanova, N. V., Karpova, A., Liang, W. W., Strzalkowski, A., Chen, S., Li, Y., Southard-Smith, A. N., Iglesia, M. D., Wendl, M. C., Jayasinghe, R. G., Liu, J., Song, Y., Cao, S., Houston, A., Liu, X., Wyczalkowski, M. A., Lu, R. J. H., Caravan, W., Shinkle, A., Naser Al Deen, N., & 24 others, Nov 9 2023, In: Nature. 623, 7986, p. 432-441 10 p.

First-in-Human Evaluation of Safety and Dosimetry of 64Cu-LLP2A for PET Imaging

Laforest, R., Ghai, A., Fraum, T. J., Oyama, R., Frye, J., Kaemmerer, H., Gaehle, G., Voller, T., Mpoy, C., Rogers, B. E., Fiala, M., Shoghi, K. I., Achilefu, S., Rettig, M., Vij, R., DiPersio, J. F., Schwarz, S., Shokeen, M. & Dehdashti, F., Feb 1 2023, In: Journal of Nuclear Medicine. 64, 2

Flotetuzumab and other T-cell immunotherapies upregulate MHC class II expression on acute myeloid leukemia cells

Rimando, J. C., Chendamarai, E., Rettig, M. P., Jayasinghe, R., Christopher, M. J., Ritchey, J. K., Christ, S., Kim, M. Y., Bonvini, E. & DiPersio, J. F., Apr 6 2023, In: Blood. 141, 14, p. 1718-1723 6 p.
Research output: Contribution to journal › Article › peer-review

Genomic landscape of TP53-mutated myeloid malignancies

Abel, H. J., Oetjen, K. A., Miller, C. A., Ramakrishnan, S. M., Day, R. B., Helton, N. M., Fronick, C. C., Fulton, R. S., Heath, S. E., Tarnawsky, S. P., Srivatsan, S. N., Duncavage, E. J., Schroeder, M. C., Payton, J. E., Spencer, D. H., Walter, M. J., Westervelt, P., DiPersio, J. F., Ley, T. J. & Link, D. C., Aug 16 2023, In: Blood Advances. 7, 16, p. 4586-4598 13 p.

Hematopoietic stem cell mobilization for allogeneic stem cell transplantation by motixafortide, a novel CXCR4 inhibitor

Crees, Z. D., Rettig, M. P., Bashey, A., Devine, S. M., Jaglowski, S., Wan, F., Zhou, A., Harding, M., Vainstein-Haras, A., Sorani, E., Gliko-Kabir, I., Grossman, B. J., Westervelt, P., DiPersio, J. F. & Uy, G. L., Sep 26 2023, In: Blood Advances. 7, 18, p. 5210-5214 5 p.

Immune Adjuvant Therapy With Interleukin-7 in a Lymphopenic Patient With Aplastic Anemia and Mucormycosis

Crees, Z. D., Patel, D. A., Dram, A., Kim, M., Bern, M. D., Eberly, A. R., Augustin, K., Hotchkiss, R. S. & Dipersio, J. F., Oct 19 2023, In: Critical Care Explorations. 5, 10, p. E0990

Innovations in hematopoietic stem-cell mobilization: a review of the novel CXCR4 inhibitor motixafortide

Crees, Z. D., Rettig, M. P. & DiPersio, J. F., Jan 1 2023, In: Therapeutic Advances in Hematology. 14

Motixafortide and G-CSF to mobilize hematopoietic stem cells for autologous transplantation in multiple myeloma: a randomized phase 3 trial

Crees, Z. D., Rettig, M. P., Jayasinghe, R. G., Stockerl-Goldstein, K., Larson, S. M., Arpad, I., Milone, G. A., Martino, M., Stiff, P., Sborov, D., Pereira, D., Micallef, I., Moreno-Jiménez, G., Mikala, G., Coronel, M. L. P., Holtick, U., Hiemenz, J., Qazilbash, M. H., Hardy, N., Latif, T., & 12 others, Apr 2023, In: Nature medicine. 29, 4, p. 869-879 11 p.

Phase I-II Trial of Early Azacitidine after Matched Unrelated Donor Hematopoietic Cell Transplantation

Xu, Z., Choi, J., Cooper, M., King, J., Fiala, M. A., Liu, J., Pusic, I., Romee, R., Cashen, A., Jacoby, M. A., Stockerl-Goldstein, K., Abboud, C., Vij, R., Uy, G., Westervelt, P., Walter, M. J., DiPersio, J. F. & Schroeder, M. A., Nov 2023, In: Transplantation and Cellular Therapy. 29, 11, p. 699.e1-699.e9

S100A9 upregulated by IFNGR signaling blockade functions as a novel GVHD suppressor without compromising GVL in mice

Kim, S., Lim, S., Kim, B., Ritchey, J., Vij, K., Prior, J., Marsala, L., Stoner, A., Gao, F., Achilefu, S., Cooper, M. L., DiPersio, J. F. & Choi, J., Feb 23 2023, In: Blood. 141, 8, p. 945-950 6 p.

Single-Cell Discovery and Multiomic Characterization of Therapeutic Targets in Multiple Myeloma

Yao, L., Wang, J. T., Jayasinghe, R. G., O’Neal, J., Tsai, C. F., Rettig, M. P., Song, Y., Liu, R., Zhao, Y., Ibrahim, O. M., Fiala, M. A., Fortier, J. M., Chen, S., Gehrs, L., Rodrigues, F. M., Wendl, M. C., Kohnen, D., Shinkle, A., Cao, S., Foltz, S. M., & 12 others, Apr 15 2023, In: Cancer research. 83, 8, p. 1214-1233 20 p.

The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia

Issa, G. C., Aldoss, I., DiPersio, J., Cuglievan, B., Stone, R., Arellano, M., Thirman, M. J., Patel, M. R., Dickens, D. S., Shenoy, S., Shukla, N., Kantarjian, H., Armstrong, S. A., Perner, F., Perry, J. A., Rosen, G., Bagley, R. G., Meyers, M. L., Ordentlich, P., Gu, Y., & 4 others, Mar 30 2023, In: Nature. 615, 7954, p. 920-924 5 p.

+ 2022

Assessment of Pretreatment and Posttreatment Evolution of Neurofilament Light Chain Levels in Patients Who Develop Immune Effector Cell-Associated Neurotoxicity Syndrome

Butt OH, Zhou AY, Caimi PF, Luckett PH, Wisch JK, Derenoncourt P, Lee K, Wu GF, de Lima MJG, Campian JL, Frank MJ, DiPersio JF, Ghobadi A, Ances BM . JAMA Oncol 2022 Nov 1;8(11):1652-1657

The Role of Allogeneic Transplant for Adult Ph+ ALL in CR1 With Complete Molecular Remission: A Retrospective Analysis

Ghobadi A, Slade M, Kantarjian H, Alvarenga J, Aldoss I, Mohammed KA, Jabbour E, Faramand R, Shah B, Locke F, Fingrut W, Park JH, Short NJ, Gao F, Uy GL, Westervelt P, DiPersio JF, Champlin RE, Al Malki MM, Ravandi F, Kebriaei P. Blood 2022 Nov 17;140(20):2101-2112

Chimeric Antigen Receptor T Cell Therapy Versus Hematopoietic Stem Cell Transplantation: An Evolving Perspective

Goldsmith SR, Ghobadi A, DiPersio JF, Hill B, Shadman M, Jain T Transplant Cell Ther 2022 Nov;28(11):727-736

Ponatinib After Failure of Second-Generation Tyrosine Kinase Inhibitor in Resistant Chronic-Phase Chronic Myeloid Leukemia

Kantarjian HM, Jabbour E, Deininger M, Abruzzese E, Apperley J, Cortes J, Chuah C, DeAngelo DJ, DiPersio J, Hochhaus A, Lipton J, Nicolini FE, Pinilla-Ibarz J, Rea D, Rosti G, Rousselot P, Shah NP, Talpaz M, Srivastava S, Ren X, Mauro M. Am J Hematol 2022 Nov;97(11):1419-1426

CML-046 Dose Modification Dynamics of Ponatinib in Patients With Chronic-Phase Chronic Myeloid Leukemia From the PACE and OPTIC Trials

Apperley, J., Kantarjian, H., Deininger, M., Abruzzese, E., Cortes, J., Chuah, C., DeAngelo, D. J., DiPersio, J., Hochhaus, A., Lipton, J. H., Nicolini, F., Pinilla-Ibarz, J., Rea, D., Rosti, G., Rousselot, P., Mauro, M., Shah, N., Talpaz, M., Vorog, A., Ren, X., & 1 others, Oct 2022, In: Clinical Lymphoma, Myeloma and Leukemia. 22, p. S284-S285
Research output: Contribution to journal › Article › peer-review

Proteomic and Phosphoproteomic Landscapes of Acute Myeloid Leukemia

Kramer MH, Zhang Q, Sprung R, Day RB, Erdmann-Gilmore P, Li Y, Xu Z, Helton NM, George DR, Mi Y, Westervelt P, Payton JE, Ramakrishnan SM, Miller CA, Link DC, DiPersio JF, Walter MJ, Townsend RR, Ley TJ Blood 2022 Sep 29;140(13):1533-1548

First-In-Human Evaluation of Safety and Dosimetry of (64)Cu-LLP2A for PET Imaging

Laforest R, Ghai A, Fraum TJ, Oyama R, Frye J, Kaemmerer H, Gaehle G, Voller T, Mpoy C, Rogers BE, Fiala M, Shoghi KI, Achilefu S, Rettig M, Vij R, DiPersio JF, Schwarz S, Shokeen M, Dehdashti F. J Nucl Med 2022 Aug 25:jnumed122264349; ahead of print

Convergent Clonal Evolution of Signaling Gene Mutations Is a Hallmark of Myelodysplastic Syndrome Progression

Menssen AJ, Khanna A, Miller CA, Nonavinkere Srivatsan S, Chang GS, Shao J, Robinson J, O'Laughlin M, Fronick CC, Fulton RS, Brendel K, Heath SE, Saba R, Welch JS, Spencer DH, Payton JE, Westervelt P, DiPersio JF, Link DC, Schuelke MJ, Jacoby MA, Duncavage EJ, Ley TJ, Walter MJ. Blood Cancer Discov 2022 Jul 6;3(4):330-345

Decitabine Salvage for TP53-Mutated, Relapsed/Refractory Acute Myeloid Leukemia After Cytotoxic Induction Therapy

Ferraro F, Gruszczynska A, Ruzinova MB, Miller CA, Percival ME, Uy GL, Pusic I, Jacoby MA, Christopher MJ, Kim MY, Westervelt P, Cashen AF, Schroeder MA, DiPersio JF, Abboud CN, Wartman LD, Gao F, Link DC, Ley TJ, Welch JS. Haematologica 2022 Jul 1;107(7):1709-1713

Safety Analysis of Patients Who Received Ruxolitinib for Steroid Refractory Acute or Chronic Graft-Versus-Host Disease in an Expanded Access Program

Schroeder MA, Hari PN, Blithe A, Paranagama D, Bhatt V, DiPersio JF Bone Marrow Transplant 2022 Jun;57(6):975-981

A Long-Acting Interleukin-7, RhIL-7-HyFc, Enhances CAR T Cell Expansion, Persistence, and Anti-Tumor Activity

Kim MY, Jayasinghe R, Devenport JM, Ritchey JK, Rettig MP, O'Neal J, Staser KW, Kennerly KM, Carter AJ, Gao F, Lee BH, Cooper ML, DiPersio JF. Nat Commun 2022 Jun 13;13(1):3296

CS1 CAR-T Targeting the Distal Domain of CS1 (SLAMF7) Shows Efficacy in High Tumor Burden Myeloma Model Despite Fratricide of CD8+CS1 Expressing CAR-T Cells

O'Neal J, Ritchey JK, Cooper ML, Niswonger J, Sofia Gonzalez L, Street E, Rettig MP, Gladney SW, Gehrs L, Abboud R, Prior JL, Haas GJ, Jayasinghe RG, Ding L, Ghobadi A, Vij R, DiPersio JF. Leukemia 2022 Jun;36(6):1625-1634

PDXNet Portal: Patient-Derived Xenograft Model, Data, Workflow and Tool Discovery

Koc S, Lloyd MW, Grover JW, Xiao N, Seepo S, Subramanian SL, Ray M, Frech C, DiGiovanna J, Webster P, Neuhauser S, Srivastava A, Woo XY, Sanderson BJ, White B, Lott P, Dobrolecki LE, Dowst H, Evrard YA, Wallace TA, Moscow JA, Doroshow JH, Mitsiades N, Kaochar S, Pan CX, Chen MS, Carvajal-Carmona L, Welm AL, Welm BE, Lewis MT, Govindan R, Ding L, Li S, Herlyn M, Davies MA, Roth J, Meric-Bernstam F, Robinson PN, Bult CJ, Davis-Dusenbery B, Dean DA 2nd, Chuang JH PDXNet Consortium (Contributors include: DiPersio J). NAR Cancer 2022 Apr 22;4(2):zcac014

Heparanase Blockade as a Novel Dual-Targeting Therapy for COVID-19

Xiang J, Lu M, Shi M, Cheng X, Kwakwa KA, Davis JL, Su X, Bakewell SJ, Zhang Y, Fontana F, Xu Y, Veis DJ, DiPersio JF, Ratner L, Sanderson RD, Noseda A, Mollah S, Li J, Weilbaecher KN. J Virol 2022 Apr 13;96(7):e0005722

Focal Disruption of DNA Methylation Dynamics at Enhancers in IDH Mutant AML Cells

Wilson ER, Helton NM, Heath SE, Fulton RS, Payton JE, Welch JS, Walter MJ, Westervelt P, DiPersio JF, Link DC, Miller CA, Ley TJ, Spencer DH. Leukemia 2022 Apr;36(4):935-945

Mouse Models of Graft-Versus-Host Disease

Patel DA, Schroeder MA, Choi J, DiPersio JF. Methods Cell Biol 2022;168:41-66

Machine Learning-Based Scoring Models to Predict Hematopoietic Stem Cell Mobilization in Allogeneic Donors

Xiang J, Shi M, Fiala MA, Gao F, Rettig MP, Uy GL, Schroeder MA, Weilbaecher KN, Stockerl-Goldstein KE, Mollah S, DiPersio JF Blood Adv 2022 Apr 12;6(7):1991-2000

MITI Minimum Information Guidelines for Highly Multiplexed Tissue Images

Schapiro D, Yapp C, Sokolov A, Reynolds SM, Chen YA, Sudar D, Xie Y, Muhlich J, Arias-Camison R, Arena S, Taylor AJ, Nikolov M, Tyler M, Lin JR, Burlingame EA, Chang YH, Farhi SL, Thorsson V, Venkatamohan N, Drewes JL, Pe'er D, Gutman DA, Herrmann MD, Gehlenborg N, Bankhead P, Roland JT, Herndon JM, Snyder MP, Angelo M, Nolan G, Swedlow JR, Schultz N, Merrick DT, Mazzili SA, Cerami E, Rodig SJ, Santagata S, Sorger PK. Human Tumor Atlas Network (Contributors include: DiPersio J) Nat Methods 2022 Mar;19(3):262-267

Systemic IL-15 Promotes Allogeneic Cell Rejection in Patients Treated With Natural Killer Cell Adoptive Therapy

Berrien-Elliott MM, Becker-Hapak M, Cashen AF, Jacobs M, Wong P, Foster M, McClain E, Desai S, Pence P, Cooley S, Brunstein C, Gao F, Abboud CN, Uy GL, Westervelt P, Jacoby MA, Pusic I, Stockerl-Goldstein KE, Schroeder MA, DiPersio JF, Soon-Shiong P, Miller JS, Fehniger TA Blood 2022 Feb 24;139(8):1177-1183

Hematopoietic Cell Transplantation Donor-Derived Memory-Like NK Cells Functionally Persist After Transfer Into Patients With Leukemia

Berrien-Elliott MM, Foltz JA, Russler-Germain DA, Neal CC, Tran J, Gang M, Wong P, Fisk B, Cubitt CC, Marin ND, Zhou AY, Jacobs MT, Foster M, Schappe T, McClain E, Kersting-Schadek S, Desai S, Pence P, Becker Hapak M, Eisele J, Mosior M, Marsala L, Griffith OL, Griffith M, Khan SM, Spencer DH, DiPersio JF, Romee R, Uy GL, Abboud CN, Ghobadi A, Westervelt P, Stockerl-Goldstein K, Schroeder MA, Wan F, Lie WR, Soon Shiong P, Petti AA, Cashen AF, Fehniger TA. Sci Transl Med 2022 Feb 23;14(633):eabm1375

Liposomal Phytohemagglutinin: In Vivo T-Cell Activator as a Novel Pan-Cancer Immunotherapy

Alhallak K, Sun J, Muz B, Jeske A, O'Neal J, Ritchey JK, Achilefu S, DiPersio JF, Azab AK. J Cell Mol Med 2022 Feb;26(3):940-944

Upfront Alternative Donor Transplant Versus Immunosuppressive Therapy in Patients With Severe Aplastic Anemia Who Lack a Fully HLA-Matched Related Donor: Systematic Review and Meta-Analysis of Retrospective Studies, on Behalf of the Severe Aplastic Anemia Working Party of the European Group for Blood and Marrow Transplantation

Alotaibi H, Aljurf M, de Latour R, Alfayez M, Bacigalupo A, Fakih RE, Schrezenmeier H, Ahmed SO, Gluckman E, Iqbal S, Höchsmann B, Halkes C, de la Fuente J, Alshehry N, Cesaro S, Passweg J, Dufour C, Risitano AM, DiPersio J, Motabi I. Transplant Cell Ther 2022 Feb;28(2):105e1-105e7

Genetic and Transcriptional Contributions to Relapse in Normal Karyotype Acute Myeloid Leukemia

Petti AA, Khan SM, Xu Z, Helton N, Fronick CC, Fulton R, Ramakrishnan SM, Nonavinkere Srivatsan S, Heath SE, Westervelt P, Payton JE, Walter MJ, Link DC, DiPersio J, Miller C, Ley TJ. Blood Cancer Discov 2022 Jan;3(1):32-49

Ablation of VLA4 in Multiple Myeloma Cells Redirects Tumor Spread and Prolongs Survival

Hathi D, Chanswangphuwana C, Cho N, Fontana F, Maji D, Ritchey J, O'Neal J, Ghai A, Duncan K, Akers WJ, Fiala M, Vij R, DiPersio JF, Rettig M, Shokeen M. Sci Rep 2022 Jan 7;12(1):30

Increased Early Mortality After Fludarabine and Melphalan Conditioning With Peripheral Blood Grafts in Haploidentical Hematopoietic Cell Transplantation With Post-Transplant Cyclophosphamide

Eastburg L, Russler-Germain DA, DiPersio JF, Fountaine T, Andolina JR, Abboud R, Huselton E. Leuk Lymphoma 2022 Jan;63(1):222-226

Baricitinib Prevents GvHD by Increasing Tregs Via JAK3 and Treats Established GvHD by Promoting Intestinal Tissue Repair Via EGFR

Kim S, Ashami K, Lim S, Staser K, Vij K, Santhanam S, Ritchey J, Peterson S, Gao F, Ciorba MA, Cooper ML, DiPersio JF, Choi J. Leukemia 2022 Jan;36(1):292-295

+ 2021

Immunosuppression and Outcomes in Adult Patients With De Novo Acute Myeloid Leukemia With Normal Karyotypes

Ferraro F, Miller CA, Christensen KA, Helton NM, O'Laughlin M, Fronick CC, Fulton RS, Kohlschmidt J, Eisfeld AK, Bloomfield CD, Ramakrishnan SM, Day RB, Wartman LD, Uy GL, Welch JS, Christopher MJ, Heath SE, Baty JD, Schuelke MJ, Payton JE, Spencer DH, Rettig MP, Link DC, Walter MJ, Westervelt P, DiPersio JF, Ley TJ. Proc Natl Acad Sci U S A 2021 Dec 7;118(49):e2116427118

Antibody-drug conjugates plus Janus kinase inhibitors enable MHC-mismatched allogeneic hematopoietic stem cell transplantation

Stephen P. Persaud, Julie K. Ritchey, Sena Kim, Sora Lim, Peter G. Ruminski, Matthew L. Cooper, Michael P. Rettig, Jaebok Choi, and John F. DiPersio. JCI 2021 Nov 2; 131(24):e145501

Combination of Dociparstat Sodium (DSTAT), a CXCL12/CXCR4 Inhibitor, With Azacitidine for the Treatment of Hypomethylating Agent Refractory AML and MDS

Huselton E, Rettig MP, Campbell K, Cashen AF, DiPersio JF, Gao F, Jacoby MA, Pusic I, Romee R, Schroeder MA, Uy GL, Marcus S, Westervelt P. Leuk Res 2021 Nov;110:106713

3D Tissue Engineered Plasma Cultures Support Leukemic Proliferation and Induces Drug Resistance

Alhallak K, de la Puente P, Jeske A, Sun J, Muz B, Rettig MP, Sahin I, Weisberg EL, Griffin JD, Reagan JL, DiPersio JF, Azab AK. Leuk Lymphoma 2021 Oct;62(10):2457-2465

A Pilot Study of 3D Tissue-Engineered Bone Marrow Culture as a Tool to Predict Patient Response to Therapy in Multiple Myeloma

Alhallak K, Jeske A, de la Puente P, Sun J, Fiala M, Azab F, Muz B, Sahin I, Vij R, DiPersio JF, Azab AK. Sci Rep 2021 Sep 29;11(1):19343

In Vivo Quantitative Assessment of Therapeutic Response to Bortezomib Therapy in Disseminated Animal Models of Multiple Myeloma With [(18)F]FDG and [(64)Cu]Cu-LLP2A PET

Ghai A, Fettig N, Fontana F, DiPersio J, Rettig M, O'Neal J, Achilefu S, Shoghi KI, Shokeen M. EJNMMI Res 2021 Sep 29;11(1):97:1186

Nanoparticle T Cell Engagers for the Treatment of Acute Myeloid Leukemia

Alhallak K, Sun J, Muz B, Jeske A, Yavner J, Bash H, Park C, Lubben B, Adebayo O, Achilefu S, DiPersio JF, Azab AK. Oncotarget 2021 Sep 14;12(19):1878-1885

Comprehensive Characterization of 536 Patient-Derived Xenograft Models Prioritizes Candidates For Targeted Treatment

Sun H, Cao S, Mashl RJ, Mo CK, Zaccaria S, Wendl MC, Davies SR, Bailey MH, Primeau TM, Hoog J, Mudd JL, Dean DA 2nd, Patidar R, Chen L, Wyczalkowski MA, Jayasinghe RG, Rodrigues FM, Terekhanova NV, Li Y, Lim KH, Wang-Gillam A, Van Tine BA, Ma CX, Aft R, Fuh KC, Schwarz JK, Zevallos JP, Puram SV, DiPersio JF, Davis-Dusenbery B, Ellis MJ, Lewis MT, Davies MA, Herlyn M, Fang B, Roth JA, Welm AL, Welm BE, Meric-Bernstam F, Chen F, Fields RC, Li S, Govindan R, Doroshow JH, Moscow JA, Evrard YA, Chuang JH, Raphael BJ, Ding L. NCI PDXNet Consortium. Nat Commun 2021 Aug 24;12(1):5086

CD7-Deleted Hematopoietic Stem Cells Can Restore Immunity After CAR T Cell Therapy

Kim MY, Cooper ML, Jacobs MT, Ritchey JK, Hollaway J, Fehniger TA, DiPersio JF. JCI Insight 2021 Aug 23;6(16):e149819

Nanoparticle T-Cell Engagers as a Modular Platform for Cancer Immunotherapy

Alhallak K, Sun J, Wasden K, Guenthner N, O'Neal J, Muz B, King J, Kohnen D, Vij R, Achilefu S, DiPersio JF, Azab AK. Leukemia 2021 Aug;35(8):2346-2357

Conservation of Copy Number Profiles During Engraftment and Passaging of Patient-Derived Cancer Xenografts

Woo XY, Giordano J, Srivastava A, Zhao ZM, Lloyd MW, de Bruijn R, Suh YS, Patidar R, Chen L, Scherer S, Bailey MH, Yang CH, Cortes-Sanchez E, Xi Y, Wang J, Wickramasinghe J, Kossenkov AV, Rebecca VW, Sun H, Mashl RJ, Davies SR, Jeon R, Frech C, Randjelovic J, Rosains J, Galimi F, Bertotti A, Lafferty A, O'Farrell AC, Modave E, Lambrechts D, Ter Brugge P, Serra V, Marangoni E, El Botty R, Kim H, Kim JI, Yang HK, Lee C, Dean DA 2nd, Davis-Dusenbery B, Evrard YA, Doroshow JH, Welm AL, Welm BE, Lewis MT, Fang B, Roth JA, Meric-Bernstam F, Herlyn M, Davies MA, Ding L, Li S, Govindan R, Isella C, Moscow JA, Trusolino L, Byrne AT, Jonkers J, Bult CJ, Medico E, Chuang JH. PDXNet Consortium (Contributors include: DiPersio JF). Nat Genet 2021 Jan;53(1):86-99

Co-Evolution of Tumor and Immune Cells During Progression of Multiple Myeloma

Liu R, Gao Q, Foltz SM, Fowles JS, Yao L, Wang JT, Cao S, Sun H, Wendl MC, Sethuraman S, Weerasinghe A, Rettig MP, Storrs EP, Yoon CJ, Wyczalkowski MA, McMichael JF, Kohnen DR, King J, Goldsmith SR, O'Neal J, Fulton RS, Fronick CC, Ley TJ, Jayasinghe RG, Fiala MA, Oh ST, DiPersio JF, Vij R, Ding L. Nat Commun 2021 May 7;12(1):2559

Highlights in Chronic Graft-Vs-Host Disease From the 62nd American Society of Hematology Annual Meeting and Exposition: Commentary

DiPersio JF. Clin Adv Hematol Oncol 2021 Feb;19 Suppl 8(2):20-23

Biology of Disease Relapse in Myeloid Disease: Implication for Strategies to Prevent and Treat Disease Relapse After Stem-Cell Transplantation

Rimando JC, Christopher MJ, Rettig MP, DiPersio JF. J Clin Oncol 2021 Feb 10;39(5):386-396

Genome Sequencing as an Alternative to Cytogenetic Analysis in Myeloid Cancers

Duncavage EJ, Schroeder MC, O'Laughlin M, Wilson R, MacMillan S, Bohannon A, Kruchowski S, Garza J, Du F, Hughes AEO, Robinson J, Hughes E, Heath SE, Baty JD, Neidich J, Christopher MJ, Jacoby MA, Uy GL, Fulton RS, Miller CA, Payton JE, Link DC, Walter MJ, Westervelt P, DiPersio JF, Ley TJ, Spencer DH. N Engl J Med 2021 Mar 11;384(10):924-935

A Phase I Trial Evaluating the Effects of Plerixafor, G-CSF, and Azacitidine for the Treatment of Myelodysplastic Syndromes

Huselton E, Rettig MP, Fletcher T, Ritchey J, Gehrs L, McFarland K, Christ S, Eades WC, Trinkaus K, Romee R, Kulkarni S, Ghobadi A, Abboud C, Cashen AF, Stockerl-Goldstein K, Uy GL, Vij R, Westervelt P, DiPersio JF, Schroeder MA. Leuk Lymphoma 2021 Jun;62(6):1441-1449

VLA4-Targeted Nanoparticles Hijack Cell Adhesion-Mediated Drug Resistance to Target Refractory Myeloma Cells and Prolong Survival

Fontana F, Scott MJ, Allen JS, Yang X, Cui G, Pan D, Yanaba N, Fiala MA, O'Neal J, Schmieder-Atteberry AH, Ritchey J, Rettig M, Simons K, Fletcher S, Vij R, DiPersio JF, Lanza GM. Clin Cancer Res 2021 Apr 1;27(7):1974-1986

Impact of a 40-Gene Targeted Panel Test on Physician Decision Making for Patients With Acute Myeloid Leukemia

Barnell EK, Newcomer KF, Skidmore ZL, Krysiak K, Anderson SR, Wartman LD, Oh ST, Welch JS, Stockerl-Goldstein KE, Vij R, Cashen AF, Pusic I, Westervelt P, Abboud CN, Ghobadi A, Uy GL, Schroeder MA, DiPersio JF, Politi MC, Spencer DH, Duncavage EJ, Ley TJ, Griffith M, Jacoby MA, Griffith OL. JCO Precis Oncol 2021 Jan 14;5

BL-8040 CXCR4 Antagonist Is Safe and Demonstrates Antileukemic Activity in Combination With Cytarabine for the Treatment of Relapsed/Refractory Acute Myelogenous Leukemia: An Open-Label Safety and Efficacy Phase 2a Study

Borthakur G, Ofran Y, Tallman MS, Foran J, Uy GL, DiPersio JF, Showel MM, Shimoni A, Nagler A, Rowe JM, Altman JK, Abraham M, Peled A, Shaw S, Bohana-Kashtan O, Sorani E, Pereg Y, Foley-Comer A, Oberkovitz G, Lustig TM, Glicko-Kabir I, Aharon A, Vainstein-Haras A, Kadosh SE, Samara E, Al-Rawi AN, Pemmaraju N, Bueso-Ramos C, Cortes JE, Andreeff M. Cancer 2021 Apr 15;127(8):1246-1259

Development of [(89)Zr]DFO-Elotuzumab for ImmunoPET Imaging of CS1 in Multiple Myeloma

Ghai A, Zheleznyak A, Mixdorf M, O'Neal J, Ritchey J, Rettig M, DiPersio, J, Shokeen M, Achilefu S, Eur J Nucl Med Mol Imaging 2021 May;48(5):1302-1311

Can Planned CD34+ Stem Cell Boost Prevent Poor Graft Function After Peripheral Blood Haploidentical Hematopoietic Transplantation?

Abboud R, Slade M, Abboud C, DiPersio JF. Leuk Lymphoma 2021 Mar;62(3):749-751

Flotetuzumab as Salvage Immunotherapy for Refractory Acute Myeloid Leukemia

Uy GL, Aldoss I, Foster MC, Sayre PH, Wieduwilt MJ, Advani AS, Godwin JE, Arellano ML, Sweet KL, Emadi A, Ravandi F, Erba HP, Byrne M, Michaelis L, Topp MS, Vey N, Ciceri F, Carrabba MG, Paolini S, Huls GA, Jongen-Lavrencic M, Wermke M, Chevallier P, Gyan E, Recher C, Stiff PJ, Pettit KM, Lowenberg B, Church SE, Anderson E, Vadakekolathu J, Santaguida M, Rettig MP, Muth J, Curtis T, Fehr E, Guo K, Zhao J, Bakkacha O, Jacobs K, Tran K, Kaminker P, Kostova M, Bonvini E, Walter RB, Davidson-Moncada JK, Rutella S, DiPersio JF. Blood 2021 Feb 11;137(6):751-762

+ 2020

Hematopoeitic Cell Transplantation and CAR T-Cell Therapy: Complements or Competitors?

Goldsmith SR, Ghobadi A, DiPersio JF. Front Oncol 2020 Dec 22;10:608916

VLA4-Nanoparticles Hijack Cell Adhesion Mediated Drug Resistance (CAM-DR) to Target Refractory Myeloma Cells and Prolong Survival

Fontana F, Scott MJ, Allen JS, Yang X, Cui G, Pan D, Yanaba N, Fiala MA, O'Neal J, Schmieder-Atteberry AH, Ritchey J, Rettig M, Simons K, Fletcher S, Vij R, DiPersio J, Lanza G. Clin Cancer Res 2020 Dec 22; (Epub ahead of print)

The Effect of Donor Type on Outcomes in Adults With Acute Myeloid Leukemia After Reduced-Intensity Hematopoietic Peripheral Blood Cell Transplant - A Retrospective Study

Rashid N, Slade M, Abboud R, Gao F, DiPersio JF, Westervelt P, Uy G, Stockerl-Goldstein K, Romee R, Schroeder MA. Transpl Int 2020 Sep;33(9):1089-1098

Borthakur G, Ofran Y, Tallman MS, Foran J, Uy GL, DiPersio JF, Showel MM, Shimoni A, Nagler A, Rowe JM, Altman JK, Abraham M, Peled A, Shaw S, Bohana-Kashtan O, Sorani E, Pereg Y, Foley-Comer A, Oberkovitz G, Lustig TM, Glicko-Kabir I, Aharon A, Vainstein-Haras A, Kadosh SE, Samara E, Al-Rawi AN, Pemmaraju N, Bueso-Ramos C, Cortes JE, Andreeff M. Cancer 2020 Dec 3; (Epub ahead of print)

Multidimensional Analyses of Donor Memory-Like NK Cells Reveal New Associations With Response After Adoptive Immunotherapy for Leukemia

Berrien-Elliott MM, Cashen AF, Cubitt CC, Neal CC, Wong P, Wagner JA, Foster M, Schappe T, Desai S, McClain E, Becker-Hapak M, Foltz JA, Cooper ML, Jaeger N, Srivatsan SN, Gao F, Romee R, Abboud CN, Uy GL, Westervelt P, Jacoby MA, Pusic I, Stockerl-Goldstein KE, Schroeder MA, DiPersio J, Fehniger TA. Cancer Discov 2020 Dec;10(12):1854-1871

Tumor Microenvironment-Targeted Nanoparticles Loaded With Bortezomib and ROCK Inhibitor Improve Efficacy in Multiple Myeloma

Federico C, Alhallak K, Sun J, Duncan K, Azab F, Sudlow GP, de la Puente P, Muz B, Kapoor V, Zhang L, Yuan F, Markovic M, Kotsybar J, Wasden K, Guenthner N, Gurley S, King J, Kohnen D, Salama NN, Thotala D, Hallahan DE, Vij R, DiPersio JF, Achilefu S, Azab AK. Nat Commun 2020 Nov 27;11(1):6037

A Pilot Study of Lenalidomide Maintenance Therapy After Autologous Transplantation in Relapsed or Refractory Classical Hodgkin Lymphoma

Shea L, Watkins MP, Wan F, Cashen AF, Wagner-Johnston ND, Jacoby MA, Abboud CN, DiPersio JF, Hurd DD, Jaglowski SM, Bartlett NL, Fehniger TA. Biol Blood Marrow Transplant 2020 Dec;26(12):2223-2228

CAR-Modified Memory-Like NK Cells Exhibit Potent Responses to NK-Resistant Lymphomas

Gang M, Marin ND, Wong P, Neal CC, Marsala L, Foster M, Schappe T, Meng W, Tran J, Schaettler M, Davila M, Gao F, Cashen AF, Bartlett NL, Mehta-Shah N, Kahl BS, Kim MY, Cooper ML, DiPersio JF, Berrien-Elliott MM, Fehniger TA. Blood 2020 Nov 12;136(20):2308-2318

Development of [(89)Zr]DFO-Elotuzumab for ImmunoPET Imaging of CS1 in Multiple Myeloma

Ghai A, Zheleznyak A, Mixdorf M, O'Neal J, Ritchey J, Rettig M, DiPersio J, Shokeen M, Achilefu S. Eur J Nucl Med Mol Imaging 2020 Nov 11; (Epub ahead of print)

Can Planned CD34+ Stem Cell Boost Prevent Poor Graft Function After Peripheral Blood Haploidentical Hematopoietic Transplantation?

Abboud R, Slade M, Abboud C, DiPersio JF. Leuk Lymphoma 2020 Nov 2:1-3; (Epub ahead of print)

Selective Targeting of Alpha4beta1 Integrin Attenuates Murine Graft Versus Host Disease

Alahmari B, Cooper ML, Vij K, Ritchey J, Ruminski P, Gao F, Choi J, DiPersio JF. Leukemia 2020 Nov;34(11):3100-3104

TP53 Abnormalities Correlate With Immune Infiltration and Associate With Response to Flotetuzumab Immunotherapy in AML

Vadakekolathu J, Lai C, Reeder S, Church SE, Hood T, Lourdusamy A, Rettig MP, Aldoss I, Advani AS, Godwin J, Wieduwilt MJ, Arellano M, Muth J, Yau TO, Ravandi F, Sweet K, Altmann H, Foulds GA, Stolzel F, Middeke JM, Ciciarello M, Curti A, Valk PJM, Lowenberg B, Gojo I, Bornhauser M, DiPersio JF, Davidson-Moncada JK, Rutella S. Blood Adv 2020 Oct 27;4(20):5011-5024

Targeting CXCR4 in AML and ALL

Cancilla D, Rettig MP, DiPersio JF. Front Oncol 2020 Sep 4;10:1672

Immunotherapy for T-Cell ALL and T-Cell NHL

DiPersio JF, Staser K, Cooper M. Clin Lymphoma Myeloma Leuk 2020 Sep;20 Suppl 1:S56-S58

Selinexor Combined With Cladribine, Cytarabine, and Filgrastim in Relapsed or Refractory Acute Myeloid Leukemia

Abboud R, Chendamarai E, Rettig MP, Trinkaus KM, Riedell PA, Abboud CN, Ghobadi A, Pusic I, Stockerl-Goldstein K, Schroeder MA, Vij R, Westervelt P, DiPersio JF, Uy GL. Haematologica 2020 Aug;105(8):e404-e407

Interleukin-15 Superagonist (N-803) Treatment of PML and JCV in a Post-Allogeneic Hematopoietic Stem Cell Transplant Patient

Oza A, Rettig MP, Powell P, O'Brien K, Clifford DB, Ritchey J, Gehrs L, Hollaway J, Major E, Fehniger TA, Miller CA, Soon-Shiong P, Rock A, DiPersio JF. Blood Adv 2020 Jun 9;4(11):2387-2391

A Phase 1 Trial of Itacitinib, a Selective JAK1 Inhibitor, in Patients With Acute Graft-Versus-Host Disease

Schroeder MA, Khoury HJ, Jagasia M, Ali H, Schiller GJ, Staser K, Choi J, Gehrs L, Arbushites MC, Yan Y, Langmuir P, Srinivas N, Pratta M, Perales MA, Chen YB, Meyers G, DiPersio JF. Blood Adv 2020 Apr 28;4(8):1656-1669

Insights Into the Role of the JAK/STAT Signaling Pathway in Graft-Versus-Host Disease

Abboud R, Choi J, Ruminski P, Schroeder MA, Kim S, Abboud CN, DiPersio JF. Ther Adv Hematol 2020 Jun 2;11:2040620720914489

Immune Landscapes Predict Chemotherapy Resistance and Immunotherapy Response in Acute Myeloid Leukemia

Vadakekolathu J, Minden MD, Hood T, Church SE, Reeder S, Altmann H, Sullivan AH, Viboch EJ, Patel T, Ibrahimova N, Warren SE, Arruda A, Liang Y, Smith TH, Foulds GA, Bailey MD, Gowen-MacDonald J, Muth J, Schmitz M, Cesano A, Pockley AG, Valk PJM, Lowenberg B, Bornhauser M, Tasian SK, Rettig MP, Davidson-Moncada JK, DiPersio JF, Rutella S. Sci Transl Med 2020 Jun 3;12(546)

Ruxolitinib for Steroid-Refractory Acute Graft-Versus-Host Disease

Toama W, Fiala MA, Pusic I, Westervelt P, DiPersio JF, Schroeder MA. Transpl Int 2020 Feb;33(2):244-246

The Predicted Indirectly Recognizable HLA Epitopes (PIRCHE) Score for HLA Class I Graft-Versus-Host Disparity Is Associated With Increased Acute Graft-Versus-Host Disease in Haploidentical Transplantation With Post-Transplantation Cyclophosphamide

Rimando J, Slade M, DiPersio JF, Westervelt P, Gao F, Liu C, Romee R. Biol Blood Marrow Transplant 2020 Jan;26(1):123-131

Engraftment of Rare, Pathogenic Donor Hematopoietic Mutations in Unrelated Hematopoietic Stem Cell Transplantation

Wong WH, Bhatt S, Trinkaus K, Pusic I, Elliott K, Mahajan N, Wan F, Switzer GE, Confer DL, DiPersio JF, Pulsipher MA, Shah NN, Sees J, Bystry A, Blundell JR, Shaw BE, Druley TE. Sci Transl Med 2020 Jan 15;12(526)

The Use of Ruxolitinib for Acute Graft-Versus-Host Disease Developing After Solid Organ Transplantation

Jacobs MT, Olson M, Ferreira BP, Jin RU, Hachem R, Byers D, Witt C, Ghobadi A, DiPersio JF, Pusic I. Am J Transplant 2020 Feb;20(2):589-592

+ 2019

Mobilized Peripheral Blood: An Updated Perspective

Karpova D, Rettig MP, DiPersio JF. F1000Res 2019 Dec 20;8

Resolution of Secondary Hemophagocytic Lymphohistiocytosis After Treatment With the JAK1/2 Inhibitor Ruxolitinib

Goldsmith SR, Saif Ur Rehman S, Shirai CL, Vij KR, DiPersio JF. Blood Adv 2019 Dec 10;3(23):4131-4135

Chimeric Antigen Receptor T Cells (CAR-T) for the Treatment of T-Cell Malignancies

Cooper ML, DiPersio JF. Best Pract Res Clin Haematol 2019 Dec;32(4):101097

Clinical Utilization of Chimeric Antigen Receptor T-Cells (CAR-T) in B-Cell Acute Lymphoblastic Leukemia (ALL)-An Expert Opinion From the European Society for Blood and Marrow Transplantation (EBMT) and the American Society for Blood and Marrow Transplantation (ASBMT)

Kansagra AJ, Frey NV, Bar M, Laetsch TW, Carpenter PA, Savani BN, Heslop HE, Bollard CM, Komanduri KV, Gastineau DA, Chabannon C, Perales MA, Hudecek M, Aljurf M, Andritsos L, Barrett JA, Bachanova V, Bonini C, Ghobadi A, Gill SI, Hill JA, Kenderian S, Kebriaei P, Nagler A, Maloney D, Liu HD, Shah NN, Kharfan-Dabaja MA, Shpall EJ, Mufti GJ, Johnston L, Jacoby E, Bazarbachi A, DiPersio JF, Pavletic SZ, Porter DL, Grupp SA, Sadelain M, Litzow MR, Mohty M, Hashmi SK. Bone Marrow Transplant 2019 Nov;54(11):1868-1880

GENESIS: Phase III Trial Evaluating BL-8040 + G-CSF to Mobilize Hematopoietic Cells for Autologous Transplant in Myeloma

Crees ZD, Stockerl-Goldstein KE, Vainstein A, Chen H, DiPersio JF. Future Oncol 2019 Nov;15(31):3555-3563

A Phase I Study of the Combination of Rituximab and Ipilimumab in Patients With Relapsed/Refractory B-Cell Lymphoma

Tuscano JM, Maverakis E, Groshen S, Tsao-Wei D, Luxardi G, Merleev AA, Beaven A, DiPersio JF, Popplewell L, Chen R, Kirschbaum M, Schroeder MA, Newman EM. Clin Cancer Res 2019 Dec 1;25(23):7004-7013

Use of Chimeric Antigen Receptor T Cell Therapy in Clinical Practice for Relapsed/Refractory Aggressive B Cell Non-Hodgkin Lymphoma: An Expert Panel Opinion From the American Society for Transplantation and Cellular Therapy

Jain T, Bar M, Kansagra AJ, Chong EA, Hashmi SK, Neelapu SS, Byrne M, Jacoby E, Lazaryan A, Jacobson CA, Ansell SM, Awan FT, Burns L, Bachanova V, Bollard CM, Carpenter PA, DiPersio JF, Hamadani M, Heslop HE, Hill JA, Komanduri KV, Kovitz CA, Lazarus HM, Serrette JM, Mohty M, Miklos D, Nagler A, Pavletic SZ, Savani BN, Schuster SJ, Kharfan-Dabaja MA, Perales MA, Lin Y. Biol Blood Marrow Transplant 2019 Dec;25(12):2305-2321

A Phase I Study of the Safety and Feasibility of Bortezomib in Combination With G-CSF for Stem Cell Mobilization in Patients With Multiple Myeloma

Ghobadi A, Fiala MA, Rettig MP, Schroeder MA, Uy GL, Stockerl-Goldstein KE, Westervelt P, Vij R, DiPersio JF. Clin Lymphoma Myeloma Leuk 2019 Oct;19(10):e588-e593

Plerixafor Alone for the Mobilization and Transplantation of HLA-Matched Sibling Donor Hematopoietic Stem Cells

Chen YB, Le-Rademacher J, Brazauskas R, Kiefer DM, Hamadani M, DiPersio JF, Litzow MR, Craig M, Horwitz ME, Artz AS, McClune BL, Fernandez HF, Duong HK, Kobusingye H, Proue M, Drexler RJ, Horowitz MM, Shaw BE, Miller JP, Hosoba S, Waller EK, Devine SM. Blood Adv 2019 Mar 26;3(6):875-883

Dynamic Host Immune Response in Virus-Associated Cancers

Cao S, Wylie KM, Wyczalkowski MA, Karpova A, Ley J, Sun S, Mashl RJ, Liang WW, Wang X, Johnson K, DiPersio JF, Gay H, Ratner L, Chen F, Adkins DR, Ding L. Commun Biol 2019 Mar 22;2(1):109

Immune Escape of AML Cells After Transplantation. Reply

Christopher M, DiPersio JF, Ley TJ. N Engl J Med 2019 Mar 28;380(13):1290

Shared Cell of Origin in a Patient With Erdheim-Chester Disease and Acute Myeloid Leukemia

Ghobadi A, Miller CA, Li T, O'Laughlin M, Lee YS, Ali M, Westervelt P, DiPersio JF, Wartman LD. Haematologica 2019 Aug;104(8):e373-e375

Targeting VLA4 Integrin and CXCR2 Mobilizes Serially Repopulating Hematopoietic Stem Cells

Karpova D, Rettig MP, Ritchey J, Cancilla D, Christ S, Gehrs L, Chendamarai E, Evbuomwan MO, Holt M, Zhang J, Abou-Ezzi G, Celik H, Wiercinska E, Yang W, Gao F, Eissenberg LG, Heier RF, Arnett SD, Meyers MJ, Prinsen MJ, Griggs DW, Trumpp A, Ruminski PG, Morrow DM, Bonig HB, Link DC, DiPersio JF. J Clin Invest 2019 May 14;130

Serendipity: Decitabine Monotherapy Induced Complete Molecular Response in a 77-Year-Old Patient With Acute Promyelocytic Leukemia

Abboud R, Han SY, Duncavage EJ, Cashen AF, Shirai CL, Welch JS, DiPersio JF, Abboud CN. Haematologica 2019 Apr;104(4):e170-e173

ASTCT Consensus Grading for Cytokine Release Syndrome and Neurologic Toxicity Associated With Immune Effector Cells

Lee DW, Santomasso BD, Locke FL, Ghobadi A, Turtle CJ, Brudno JN, Maus MV, Park JH, Mead E, Pavletic S, Go WY, Eldjerou L, Gardner RA, Frey N, Curran KJ, Peggs K, Pasquini M, DiPersio JF, van den Brink MRM, Komanduri KV, Grupp SA, Neelapu SS. Biol Blood Marrow Transplant 2019 Apr;25(4):625-638

Clinical Utilization of Chimeric Antigen Receptor T Cells in B Cell Acute Lymphoblastic Leukemia: An Expert Opinion From the European Society for Blood and Marrow Transplantation and the American Society for Blood and Marrow Transplantation

Kansagra AJ, Frey NV, Bar M, Laetsch TW, Carpenter PA, Savani BN, Heslop HE, Bollard CM, Komanduri KV, Gastineau DA, Chabannon C, Perales MA, Hudecek M, Aljurf M, Andritsos L, Barrett JA, Bachanova V, Bonini C, Ghobadi A, Gill SI, Hill J, Kenderian S, Kebriaei P, Nagler A, Maloney D, Liu HD, Shah NN, Kharfan-Dabaja MA, Shpall EJ, Mufti GJ, Johnston L, Jacoby E, Bazarbachi A, DiPersio JF, Pavletic SZ, Porter DL, Grupp SA, Sadelain M, Litzow MR, Mohty M, Hashmi SK. Biol Blood Marrow Transplant 2019 Mar;25(3):e76-e85

+ 2018

HLA Epitope Mismatch in Haploidentical Transplantation Is Associated With Decreased Relapse and Delayed Engraftment

Rimando J, Slade M, DiPersio JF, Westervelt P, Gao F, Liu C, Romee R. Blood Adv 2018 Dec 26;2(24):3590-3601

CiTE Antibody for AML

Rettig MP, DiPersio JF. Blood 2018 Dec 6;132(23):2425-2427

Targeting IFNGR/IL6R or Downstream JAK1/JAK2 to Control GvHD

Ashami K, DiPersio JF, Choi J. Oncotarget 2018 Nov 6;9(87):35721-35722

Selective Targeting of Histone Modification Fails to Prevent Graft Versus Host Disease After Hematopoietic Cell Transplantation

Alahmari B, Cooper M, Ziga E, Ritchey J, DiPersio JF, Choi J. PLoS One 2018 Nov 19;13(11):e0207609

Long-Term Efficacy and Safety of Dasatinib in Patients With Chronic Myeloid Leukemia in Accelerated Phase Who Are Resistant to or Intolerant of Imatinib

Ottmann O, Saglio G, Apperley JF, Arthur C, Bullorsky E, Charbonnier A, DiPersio JF, Kantarjian H, Khoury HJ, Kim DW, Healey D, Strauss L, Cortes JE. Blood Cancer J 2018 Sep 3;8(9):88

Secondary Acute Lymphoblastic Leukemia, a Retrospective Analysis From Washington University and Meta-Analysis of Published Data

Ferraro F, Gao F, Stockerl-Goldstein K, Westervelt P, DiPersio JF, Ghobadi A. Leuk Res 2018 Sep;72:86-91

Immune Escape of Relapsed AML Cells After Allogeneic Transplantation

Christopher MJ, Petti AA, Rettig MP, Miller CA, Chendamarai E, Duncavage EJ, Klco JM, Helton NM, O'Laughlin M, Fronick CC, Fulton RS, Wilson RK, Wartman LD, Welch JS, Heath SE, Baty JD, Payton JE, Graubert TA, Link DC, Walter MJ, Westervelt P, Ley TJ, DiPersio JF. N Engl J Med 2018 Dec 13;379(24):2330-2341

Mutation Clearance After Transplantation for Myelodysplastic Syndrome

Duncavage EJ, Jacoby MA, Chang GS, Miller CA, Edwin N, Shao J, Elliott K, Robinson J, Abel H, Fulton RS, Fronick CC, O'Laughlin M, Heath SE, Brendel K, Saba R, Wartman LD, Christopher MJ, Pusic I, Welch JS, Uy GL, Link DC, DiPersio JF, Westervelt P, Ley TJ, Trinkaus K, Graubert TA, Walter MJ. N Engl J Med 2018 Sep 13;379(11):1028-1041

Integrative Omics Analyses Broaden Treatment Targets in Human Cancer

Sengupta S, Sun SQ, Huang KL, Oh C, Bailey MH, Varghese R, Wyczalkowski MA, Ning J, Tripathi P, McMichael JF, Johnson KJ, Kandoth C, Welch J, Ma C, Wendl MC, Payne SH, Fenyo D, Townsend RR, DiPersio JF, Chen F, Ding L. Genome Med 2018 Jul 27;10(1):60

Effect of Antihuman T Lymphocyte Globulin on Immune Recovery After Myeloablative Allogeneic Stem Cell Transplantation With Matched Unrelated Donors: Analysis of Immune Reconstitution in a Double-Blind Randomized Controlled Trial

Gooptu M, Kim HT, Chen YB, Rybka W, Artz A, Boyer M, Johnston L, McGuirk J, Shea TC, Jagasia M, Shaughnessy PJ, Reynolds CG, Fields M, Alyea EP, Ho VT, Glavin F, DiPersio JF, Westervelt P, Ritz J, Soiffer RJ. Biol Blood Marrow Transplant 2018 Nov;24(11):2216-2223

Ixazomib, an Oral Proteasome Inhibitor, Induces Rapid Mobilization of Hematopoietic Progenitor Cells in Mice

Ghobadi A, Rettig MP, Holt MS, Ritchey JK, Kennerly K, Chendamarai E, Eissenberg L, DiPersio JF. Blood 2018 Jun 7;131(23):2594-2596

Propensity Score Analysis of Conditioning Intensity in Peripheral Blood Haploidentical Hematopoietic Cell Transplantation

Huselton E, Slade M, Trinkaus KM, DiPersio JF, Westervelt P, Romee R. Biol Blood Marrow Transplant 2018 Oct;24(10):2047-2055